Mechanism of Action: Rilpivirine works by binding to and inhibiting HIV reverse transcriptase, an enzyme crucial for the replication of the HIV virus. By blocking this enzyme, rilpivirine prevents the replication of HIV and reduces the amount of the virus in the blood.
Antiviral Activity: Rilpivirine exhibits high antiviral activity against both wild-type and mutant strains of HIV-1, including those resistant to first-generation NNRTIs.