Lornoxicam, also known as Ro 13-9297, Chlortenoxicam, TS110, is a novel non-steroidal anti-inflammatory drug (NSAID) with potent inhibitory effects on both COX-1 and COX-2 enzymes.
Basic Information
English Name: Lornoxicam
CAS Number: 70374-39-9
Molecular Formula: C13H10ClN3O4S2
Molecular Weight: 371.82
Pharmacological Action
Unlike other oxicam compounds, Lornoxicam exhibits potent inhibition of prostaglandin biosynthesis, contributing to its significant effects in relieving pain, inflammation, and fever.
Clinical Applications
Postoperative Pain Relief: Comparable to opioid analgesics such as morphine, pethidine (meperidine), and tramadol in relieving postoperative pain following gynecological or orthopedic surgeries.
Arthritis Treatment: Effective in alleviating symptoms of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute sciatica, and low back pain, similar to other NSAIDs.
