Carbetocin is a medication primarily used in obstetrics and gynecology, particularly after childbirth and cesarean section surgeries, to help enhance uterine contractions and reduce postpartum hemorrhage.
Basic Information
English Name: Carbetocin
Molecular Formula: C45H69N11O12S
Molecular Weight: 988.17
CAS Registry Number: 37025-55-1
Pharmacological Action
Carbetocin is a synthetic oxytocin analog that acts by stimulating the release of oxytocin from the posterior pituitary gland. Its mechanism of action involves binding to oxytocin receptors on uterine smooth muscles, causing uterine smooth muscle contractions, thereby enhancing uterine contractility. This medication is commonly used in obstetrics to reduce postpartum hemorrhage, often showing more pronounced effects than traditional oxytocin.
Clinical Applications
Prevention of Postpartum Hemorrhage: After childbirth or cesarean section, Carbetocin can effectively prevent the occurrence of postpartum hemorrhage.
Treatment of Postpartum Hemorrhage: For cases where postpartum hemorrhage has already occurred, Carbetocin can be used as a therapeutic agent to reduce blood loss by enhancing uterine contractions.
