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Terazosin Hydrochloride
    Publish time 2024-09-18 17:42    

CAS NO.: 63074-08-8

Terazosin Hydrochloride

Terazosin Hydrochloride, also known as Hytrin, is a selective α1-adrenoceptor antagonist primarily used in the treatment of benign prostatic hyperplasia (BPH) and mild to moderate hypertension.

Basic Information

  • Generic Name: Terazosin Hydrochloride

  • CAS Number: 63074-08-8

  • Chemical Name: 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanylcarbonyl)piperazine hydrochloride

  • Molecular Formula: C19H25N5O4·HCl (or may include additional hydration states, such as C19H25N5O4·HCl·2H2O)

  • Molecular Weight: 423.90 (or 459.93, depending on the hydration state)

Physical Properties

  • Appearance: White to off-white crystalline powder, practically odorless, slightly bitter taste

  • Solubility: Freely soluble in water

Indications

  • Benign Prostatic Hyperplasia (BPH): Terazosin Hydrochloride relaxes the smooth muscle tissue in the prostate and bladder neck, thereby improving urinary flow and reducing symptoms associated with BPH.

  • Hypertension: As a selective α1-adrenoceptor antagonist, it decreases peripheral vascular resistance, resulting in lowered blood pressure, particularly suitable for the management of mild to moderate hypertension.

In summary, Terazosin Hydrochloride (Hytrin) is an effective medication for managing benign prostatic hyperplasia and mild to moderate hypertension.