Pitavastatin Calcium, also known as Livalo, is a potent lipid-lowering medication primarily used in the treatment of hypercholesterolemia and familial hypercholesterolemia.
Basic Information
Generic Name: Pitavastatin Calcium
CAS Number: 147526-32-7
Molecular Formula: Depending on the source, it may be represented as C50H46CaF2N2O8 (molecular weight 880.98) or a related formula reflecting the salt and possible hydration state.
Appearance: White to off-white powder or solid
Pharmacological Action
Pitavastatin Calcium belongs to the class of statins, which work by inhibiting the enzyme 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase. This inhibition reduces the liver's ability to produce cholesterol, leading to improved blood cholesterol levels.
Indications
Treatment of hypercholesterolemia (high levels of cholesterol in the blood)
Management of familial hypercholesterolemia (a genetic condition characterized by high cholesterol levels)
Safety and Tolerability
Pitavastatin Calcium is generally well-tolerated with a good safety profile.
Long-term studies have not shown significant adverse effects on the central nervous system, reproductive system, or myocardial function.
Other Benefits
In addition to its lipid-lowering effects, Pitavastatin Calcium has shown potential in various other therapeutic areas, including anti-atherosclerosis, anti-asthmatic, anti-osteoarthritic, anti-tumor, neuroprotective, hepatoprotective, and nephroprotective activities.
In summary, Pitavastatin Calcium (Livalo) is an effective and well-tolerated statin medication that plays a crucial role in managing hypercholesterolemia and familial hypercholesterolemia. Its broad therapeutic potential and favorable safety profile make it an important tool in the management of cardiovascular health.
