Eltrombopag Olamine, also known as Revolade, is an orally active, non-peptide agonist of the thrombopoietin receptor. It is a key medication used in the treatment of certain blood disorders characterized by low platelet counts.
Basic Information
Generic Name: Eltrombopag Olamine
CAS Number: 496775-62-3
Molecular Formula: C29H36N6O6
Molecular Weight: 564.633 g/mol
Pharmacological Action
Eltrombopag Olamine stimulates platelet production by activating the thrombopoietin receptor, leading to an increase in platelet counts.
Clinical Applications
Indications:
It is indicated for the treatment of chronic immune thrombocytopenia (ITP) in adults and children aged 6 years and older who have had an insufficient response to previous treatments such as corticosteroids or intravenous immunoglobulin.
It is also used in patients with severe aplastic anemia (SAA) who have had an inadequate response to immunosuppressive therapy.
