Hydrocortisone Sodium Succinate

Hydrocortisone Sodium Succinate is an adrenocortical hormone drug and a salt compound of hydrocortisone. 

I. Basic Information

• English Name: Hydrocortisone Sodium Succinate

• Chemical Name: 11β,17-dihydroxy-21-(3-carboxy-1-hydroxypropoxy)pregna-4-ene-3,20-dione sodium salt

• Molecular Formula: C25H33NaO8

• Molecular Weight: 484.52

• CAS Number: 125-04-2

• EINECS Number: 204-725-5

II. Pharmacological Effects

1. Anti-inflammatory Effect: Hydrocortisone Sodium Succinate can alleviate and prevent the body's inflammatory response, thereby reducing inflammatory symptoms.

2. Immunosuppressive Effect: This medication can prevent or inhibit cell-mediated immune reactions, delayed allergic reactions, and reduce the expansion of primary immune reactions.

3. Antitoxin and Anti-shock Effect: It counteracts the stimulatory effects of bacterial endotoxins on the body, reduces cellular damage, and protects the body.

III. Indications

Hydrocortisone Sodium Succinate is mainly used for the following conditions:

• Adrenocortical insufficiency and hypopituitarism

• Allergic and inflammatory diseases

• Various acute severe bacterial infections, severe allergic diseases, rheumatic diseases, and rheumatoid diseases, etc.