Fudosteine is an expectorant medication used for the treatment of various respiratory diseases.
Basic Information
English Name: Fudosteine
Chemical Name: (-)-(R)-2-Amino-3-(3-hydroxypropylthio)propionic Acid
CAS Number: 13189-98-5
Molecular Formula: C6H13NO3S
Molecular Weight: 179.23
Pharmacological Effects
Fudosteine exerts its pharmacological effects by inhibiting the hexose monophosphate shunt metabolism in bronchial mucosal cells, thereby reducing mucus secretion. It also functions as an antitussive, expectorant, antiasthmatic, and lung ventilation improver. Specifically, its pharmacological effects include:
Inhibiting the proliferation of respiratory epithelial cells and normalizing the ratio of fucose to sialic acid in sputum.
Restoring the ciliary transport of airway secretions and promoting the excretion of sputum.
Reducing the viscosity of sputum, making it easier to expectorate.
Increasing the secretion of serous glands in the respiratory mucosa while decreasing the secretion of mucous glands.
Exhibiting anti-inflammatory effects, combating inflammation, repairing membranes, increasing the penetration of anti-infective drugs into bronchial mucosa and epithelial tissues, and enhancing the drug concentration of antibiotics in the airways.
Indications
Fudosteine is indicated for the expectorant treatment of various respiratory diseases, including:
