Appearance: White or almost white crystalline powder
Melting Point: Approximately 206°C (may vary slightly depending on purity and manufacturing process)
Solubility: Soluble in acetone, methanol, and dimethylformamide. Sparingly soluble in ethanol. Practically insoluble in water.
Density: Not specifically mentioned, but density values can be determined experimentally.
Refractive Index: Not specifically mentioned, but refractive index values can be determined experimentally.
Chemical Properties
Stability: Stable under normal conditions, but light-sensitive, air-sensitive, and hygroscopic. Should be stored in a cool, dry place, protected from light and moisture.
pH: Not specifically mentioned as a standalone property, but Furosemide is typically formulated in pharmaceutical preparations within a pH range suitable for oral or parenteral administration.
Pharmaceutical Properties
Mechanism of Action: Furosemide is a loop diuretic that acts on the ascending loop of Henle in the kidney, inhibiting the reabsorption of sodium, chloride, and water, thereby increasing urine output.
Therapeutic Effects: It is used for the treatment of edema associated with congestive heart failure, cirrhosis of the liver, and renal dysfunction. It is also used in the management of hypertension, acute pulmonary edema, and cerebral edema. Additionally, it can promote the excretion of upper urinary tract stones and accelerate the excretion of toxic substances in cases of poisoning.
