Melting Point: Not available (but typically, similar compounds may have melting points within a certain range)
Boiling Point: 601.4°C at 760 mmHg
Density: 1.249 g/cm³
Refractive Index: 1.552
Flash Point: 317.5°C
Vapor Pressure: 2.58E-15 mmHg at 25°C
Chemical Properties
Solubility: Soluble in DMSO, slightly soluble in water, and soluble in ethanol.
Stability: Stable under normal conditions, but should be stored in a cool, dry place to avoid decomposition.
pH: Not specifically mentioned, but as a pharmaceutical compound, it is likely to be formulated within a pH range suitable for oral administration.
Target and Mechanism of Action
Target: α1-adrenergic receptor (specifically α1A-AR, α1B-AR, and α1D-AR)
Mechanism of Action: Silodosin acts as a selective α1-adrenoceptor antagonist, inhibiting the contraction of smooth muscles in the prostate and bladder neck. This leads to an improvement in urinary symptoms associated with benign prostatic hyperplasia (BPH).
Uses
Silodosin is primarily used for the treatment of benign prostatic hyperplasia (BPH), providing relief from symptoms such as urinary frequency, urgency, nocturia, and difficulty in urination.
