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Terlipressin
    Publish time 2024-10-18 17:57    

CAS Number: 14636-12-5

Terlipressin

Basic Information

  • Product Name: Terlipressin

  • CAS Number: 14636-12-5

  • Molecular Formula: C52H74N16O15S2

  • Molecular Weight: 1227.372 g/mol

Physical and Chemical Properties

  • Appearance: White powder

  • Density: Approximately 1.5 ± 0.1 g/cm3 (or 1.46 g/cm3 according to some sources)

  • Boiling Point: 1824.0 ± 65.0 °C at 760 mmHg

  • Flash Point: 1056.9 ± 34.3 °C

  • Refractive Index: 1.664

  • Vapor Pressure: 0.0 ± 0.3 mmHg at 25 °C

  • Solubility: Information on solubility is not provided specifically, but it can be used in scientific research, identification, and pharmacological experiments.

Biological Activity

  • Terlipressin is a vasopressin analogue with potent vasoactive properties.

  • It is a highly selective vasopressin V1 receptor agonist.

  • It reduces splanchnic blood flow and portal pressure, thereby controlling acute variceal bleeding.

  • Terlipressin also exhibits anti-inflammatory and anti-oxidative effects.

Pharmaceutical Applications

  • It is used for the treatment of gastrointestinal and genitourinary bleeding, such as esophageal variceal bleeding, gastric and duodenal ulcers, functional and other causes of uterine bleeding, bleeding during childbirth or miscarriage, etc.

  • It can be used locally in gynecological surgeries, such as in the cervix.