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Flucloxacillin sodium
    Publish time 2024-10-14 11:20    

CAS Number: 1847-24-1

Flucloxacillin sodium

I. Basic Information

  • Product Name: Flucloxacillin Sodium

  • Chemical Formula: C19H16ClFN3NaO5S

  • Molecular Weight: 475.854 (or 476.86, with slight variations possibly due to different preparation methods or forms)

  • CAS Registry Number: 1847-24-1

  • EINECS Registry Number: 217-428-0

II. Physical Properties

  • Appearance: White solid or white powder

  • Melting Point: 176~178°C

  • Boiling Point: 677.3°C (at 760 mmHg)

  • Flash Point: 363.4°C

  • Vapor Pressure: 2.86E-19 mmHg (at 25°C)

  • Solubility: Easily soluble in water, also soluble in methanol, ethanol, or acetone with varying solubility rates. For example, the dissolution ratio in ethanol is 1:12, and in acetone is also 1:12.

III. Chemical Properties

  • Stability: Should be stored in dry, light-protected conditions, avoiding repeated freezing and thawing. In powder form, it can be stored at -25~-15°C with a longer shelf life; when dissolved in solvents, it should be stored at lower temperatures to maintain its stability.

  • Antibacterial Activity: Flucloxacillin Sodium is a semisynthetic penicillin antibiotic with high activity against Gram-positive and some Gram-negative bacteria. It is primarily used for severe infections and sepsis caused by penicillin-resistant Staphylococcus aureus, as well as various surrounding infections caused by Staphylococcus, but it is ineffective against methicillin-resistant Staphylococcus aureus (MRSA) infections.