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Losartan Potassium
    Publish time 2024-09-27 11:22    

CAS NO.: 124750-99-8

Losartan Potassium

Basic Information

  • Chinese Name: 氯沙坦钾

  • English Name: Losartan Potassium

  • CAS Number: 124750-99-8

  • Molecular Formula: C22H23ClKN6O (some sources may show C22H22ClKN6O, reflecting slight differences in notation but with the same core structure)

  • Molecular Weight: 462.01 (or 461.001, depending on the molecular formula notation)

  • EINECS Number: 200-287-4

Physical Properties

  • Melting Point: 263-265°C

  • Boiling Point: 682°C at 760 mmHg

  • Flash Point: 366.3°C

  • Vapor Pressure: 1.55E-19 mmHg at 25°C

  • Solubility: Freely soluble in water and methanol, slightly soluble in acetonitrile

Chemical Properties

  • Losartan Potassium is a potent, orally active drug that selectively binds to AT1 receptors, blocking the physiological effects of angiotensin II, thereby exerting antihypertensive effects.

Uses

  • Pharmaceutical: Primarily used in the treatment of hypertension, representing a novel class of sartan-based antihypertensive agents.

  • Research: Also used in scientific research experiments, with restrictions on use prohibiting diagnostic purposes.

Storage and Transportation

  • Storage Conditions: Store sealed, protected from light, and at low temperatures, preferably in an inert atmosphere at room temperature.

  • Transportation: Cargo packaging complies strictly with transportation instructions to avoid quality changes due to temperature fluctuations during transit.