Basic Chemical Information:

Chemical Name: Isavuconazonium Sulfate
Molecular Formula: C35H38F2N8O8S
Molecular Weight: 814.79 g/mol
CAS Number: 241479-67-4

Pharmacological Actions:

Mechanism of Action:
- Isavuconazonium sulfate is a prodrug that, once administered, is rapidly hydrolyzed to its active form, isavuconazole.
- Isavuconazole is an antifungal agent that works by inhibiting the enzyme lanosterol 14-α-demethylase, a critical enzyme in the ergosterol biosynthesis pathway.
- By disrupting ergosterol production, it weakens the fungal cell membrane, leading to increased cell permeability and ultimately fungal cell death.