Calcitonin Salmon, a peptide hormone derived from salmon, possesses significant biological activities and clinical applications.
Basic Information
English Name: Calcitonin (Salmon)
CAS Number: 47931-85-1
Molecular Formula: C145H240N44O48S2
Molecular Weight: 3431.85
Pharmacological Effects
Calcitonin Salmon, a calcium-regulating hormone, acts as a dual agonist for amylin and calcitonin receptors. Its primary pharmacological effects include:
Stimulating Bone Formation: Calcitonin Salmon enhances the activity of bone cells, such as osteoblasts, promoting the formation and mineralization of bone matrix, thereby aiding in bone growth and repair.
Inhibiting Bone Resorption: By suppressing the activity and number of osteoclasts, Calcitonin Salmon reduces bone loss and preserves bone integrity and strength.
Clinical Applications
Calcitonin Salmon is primarily used in the treatment of bone-related diseases, especially osteoporosis. Osteoporosis is a systemic skeletal disease characterized by decreased bone mass, deterioration of bone microarchitecture, increased bone fragility, and heightened fracture risk. Calcitonin Salmon effectively alleviates symptoms, improves bone density, and lowers fracture risk in osteoporosis patients.
Additionally, it can be used to treat bone pain associated with osteoporosis and as an adjunctive therapy for other bone disorders.
