Ibandronate Sodium is a highly potent nitrogen-containing bisphosphonate used primarily in the treatment of osteoporosis and other bone-related disorders.
Basic Information
English Name: Ibandronate Sodium
CAS Number: 138926-19-9
Molecular Formula: C9H22NO7P2·Na·H2O
Molecular Weight: 359.23
Clinical Applications
Osteoporosis:
As a third-generation bisphosphonate bone resorption inhibitor, Ibandronate Sodium binds to bone hydroxyapatite, inhibiting its dissolution and formation, resulting in anti-bone resorption effects.
It effectively slows bone loss, increases bone density and strength, aids in bone remodeling, and reduces the risk of fractures.
Clinical trials have shown its efficacy in treating postmenopausal osteoporosis and Paget's disease of bone.
Cancer-related Bone Metastases or Hypercalcemia of Malignancy:
Ibandronate Sodium is indicated for the relief of hypercalcemia caused by malignancy or bone metastases from cancer.
By inhibiting osteoclast-mediated bone resorption, it prevents bone loss, aids in bone remodeling, and reduces the risk of fractures.
