Clemastine Fumarate is a selective histamine H1 receptor antagonist with antihistaminic properties. It is primarily used in the treatment of allergic rhinitis, urticaria, eczema, and other allergic skin conditions.
Basic Information
CAS Number: 14976-57-9
Molecular Formula: C25H30ClNO5
Molecular Weight: 459.96
English Name: Clemastine Fumarate
Pharmacological Actions
Clemastine Fumarate competitively blocks histamine from binding to H1 receptors, thereby inhibiting the release of histamine and reducing the symptoms of allergic reactions. Its potent antihistaminic activity helps alleviate itching, sneezing, runny nose, and other allergic symptoms. Additionally, it exhibits anti-inflammatory properties by inhibiting the release of certain cytokines.
Clinical Uses
Used to treat allergic rhinitis, urticaria, eczema, and other allergic skin conditions.
May also be used in the management of asthma and other allergic diseases.
