Acitretin

Acitretin is a synthetic aromatic vitamin A analogue and the active metabolite of Etaretinate. It is primarily used in medicine to treat severe psoriasis and keratinization disorders. 

Basic Information

• English Name: Acitretin

• Chemical Formula: C21H26O3

• Molecular Weight: 326.43

• CAS Registry Number: 55079-83-9

Pharmacological Effects

• It exhibits regulatory effects on epidermal cell differentiation and proliferation.

• However, the exact mechanism of action in psoriasis and other keratinization disorders is not fully understood.

Indications

• Severe psoriasis and keratosis disorders

• Also effective for severe hidradenitis suppurativa, rosacea, Gram-negative acne, follicular keratosis, and other conditions that do not respond to conventional therapies