Dexamethasone Sodium Phosphate is an organic compound primarily used as an adrenocortical hormone drug with anti-inflammatory, anti-allergic, anti-rheumatic, and immunosuppressive effects. It is commonly prescribed for allergies and autoimmune diseases.
Basic Information
English Name: Dexamethasone Sodium Phosphate
Chemical Formula: C22H28FNa2O8P
Molecular Weight: 516.4
CAS Number: 2392-39-4
Pharmacological Actions
Anti-inflammatory Effects: Dexamethasone Sodium Phosphate reduces and prevents tissue's response to inflammation, inhibiting the accumulation of inflammatory cells at inflammatory sites and suppressing the synthesis and release of inflammatory chemical mediators.
Immunosuppressive Effects: It includes preventing or inhibiting cell-mediated immune responses, delayed-type hypersensitivity reactions, reducing the number of T lymphocytes, monocytes, and eosinophils, decreasing the binding capacity of immunoglobulins to cell surface receptors, and inhibiting the synthesis and release of interleukins.
Indications
Dexamethasone Sodium Phosphate is primarily used for allergic and autoimmune inflammatory diseases such as connective tissue diseases, active rheumatism, rheumatoid arthritis, lupus erythematosus, severe bronchial asthma, severe dermatitis, ulcerative colitis, acute leukemia, and in comprehensive treatment for some severe infections and poisonings, as well as malignant lymphoma.
