Dexamethasone Acetate is an essential glucocorticoid drug with extensive biological activities and clinical applications.
Basic Information
English Name: Dexamethasone Acetate
CAS Number: 1177-87-3
Molecular Weight: 434.5
Molecular Formula: C24H31FO6
Pharmacological Effects and Biological Activities
Pharmacological Action: Dexamethasone Acetate is a glucocorticoid receptor agonist, exhibiting a broad range of biochemical and physiological effects, including gene expression regulation, immune modulation, and induction of apoptosis in certain types of cancer cells. It also modulates the activity of the hypothalamic-pituitary-adrenal (HPA) axis, participating in the regulation of stress responses.
Biological Activities:
Anti-inflammatory: Potently inhibits inflammatory responses, reducing the release of inflammatory factors.
Immunomodulatory: Modulates immune responses, decreasing the activation and proliferation of immune cells.
Antineoplastic: Induces apoptosis and inhibits proliferation in certain types of cancer cells.
Other Activities: Demonstrates anti-proliferative, anti-apoptotic, and various other biological activities.
Clinical Applications
Dexamethasone Acetate is widely used in the treatment of various diseases due to its potent anti-inflammatory and immunomodulatory effects, including:
