Alternative Names: Perindoril, Aceon, UNII-1964X464OJ, etc.
CAS Registry Number: 107133-36-8
Molecular Formula: C23H43N3O5
Molecular Weight: 441.60 (or 441.61, slight variations may exist depending on sources)
EINECS Number: 600-798-6
Structure and Properties
Perindopril Erbumine is a long-acting angiotensin-converting enzyme (ACE) inhibitor with a complex structure containing multiple chiral centers.
Physically, it has a melting point of approximately 126-130°C and a high boiling point (e.g., 537.4°C at 760 mmHg), but specific vapor pressure and flash point data may not be readily available.
In terms of solubility, Perindopril Erbumine exhibits some solubility in water, such as 10 mg/mL.
Uses and Applications
Perindopril Erbumine is primarily used in the treatment of hypertension and congestive heart failure.
As an ACE inhibitor, it works by inhibiting the activity of angiotensin-converting enzyme, reducing the production of angiotensin II, thereby dilating blood vessels, lowering blood pressure, and improving cardiac function.
Safety and Storage
Proper temperature and humidity conditions must be maintained during storage to ensure the stability and effectiveness of Perindopril Erbumine.
Specific storage conditions may include a shelf life of 3 years at -20°C or 2 years at 4°C.
During transportation and use, it is essential to avoid exposure to high temperatures, humidity, and direct sunlight.