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Perindopril Erbumine
    Publish time 2024-09-20 14:27    

CAS NO.: 107133-36-8

Perindopril Erbumine

Basic Information

  • Chinese Name: 培哚普利

  • English Name: Perindopril Erbumine

  • Alternative Names: Perindoril, Aceon, UNII-1964X464OJ, etc.

  • CAS Registry Number: 107133-36-8

  • Molecular Formula: C23H43N3O5

  • Molecular Weight: 441.60 (or 441.61, slight variations may exist depending on sources)

  • EINECS Number: 600-798-6

Structure and Properties

  • Perindopril Erbumine is a long-acting angiotensin-converting enzyme (ACE) inhibitor with a complex structure containing multiple chiral centers.

  • Physically, it has a melting point of approximately 126-130°C and a high boiling point (e.g., 537.4°C at 760 mmHg), but specific vapor pressure and flash point data may not be readily available.

  • In terms of solubility, Perindopril Erbumine exhibits some solubility in water, such as 10 mg/mL.

Uses and Applications

  • Perindopril Erbumine is primarily used in the treatment of hypertension and congestive heart failure.

  • As an ACE inhibitor, it works by inhibiting the activity of angiotensin-converting enzyme, reducing the production of angiotensin II, thereby dilating blood vessels, lowering blood pressure, and improving cardiac function.

Safety and Storage

  • Proper temperature and humidity conditions must be maintained during storage to ensure the stability and effectiveness of Perindopril Erbumine.

  • Specific storage conditions may include a shelf life of 3 years at -20°C or 2 years at 4°C.

  • During transportation and use, it is essential to avoid exposure to high temperatures, humidity, and direct sunlight.