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Cefaclor
    Publish time 2024-09-14 16:04    

CAS NO.: 53994-73-3

Cefaclor

Basic Information

  • Chemical Name: Cefaclor, which may include a complex structural description such as (6R,7R)-7-[(R)-2-Amino-2-phenylacetamido]-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid.

  • Molecular Formula: C15H14ClN3O4S

  • Molecular Weight: 367.81

  • CAS Number: 53994-73-3 or 70356-03-5 (may vary depending on the source)

  • EINECS Number: 258-909-5 (if provided)

  • Appearance: Cefaclor is usually a white to slightly yellowish powder or crystalline powder with a faint odor. It is slightly soluble in water and practically insoluble in methanol, ethanol, chloroform, or dichloromethane.

Pharmacological Effects

  • Cefaclor is a broad-spectrum, semi-synthetic cephalosporin antibiotic that exerts its bactericidal action primarily by inhibiting bacterial cell wall synthesis.

  • It displays potent antibacterial activity against a wide range of Gram-positive and Gram-negative bacteria, including Streptococcus pneumoniae, Haemophilus influenzae, methicillin-sensitive Staphylococcus species, Streptococcus pyogenes, among others.

  • Cefaclor's broad spectrum of activity makes it suitable for the treatment of various infections caused by susceptible organisms, including respiratory infections (pharyngitis, tonsillitis, bronchitis, pneumonia, etc.), otolaryngological infections (otitis media, etc.), urinary tract infections (pyelonephritis, cystitis, etc.), skin and soft tissue infections, and others.